Course
Biology 375, Molecular Genetics
Document Type
Student Paper
Publication Date
2017
Disciplines
Bioinformatics | Biology | Molecular Genetics
Description, Abstract, or Artist's Statement
We predict that Mrub__[0759] encodes the enzyme [Meiothermus ruber Fruktokinase] (DNA coordinates [741282..742202 on the forward strand] which is the 00500 step of the Starch and Sucrose Metabolism pathway (KEGG map number [2.7.1.4]). It catalyzes the conversion of [ATP + D-fructoseADP + D-fructose 6-phosphate]. The E. coli K12 MG1655 ortholog is predicted to be b1309, which has the gene identifier [ycjM] We predict that Mrub__[ 2365] encodes the enzyme [Meiothermus ruber Fruktokinase] (DNA coordinates [2417118..2418059 on the forward strand], which is the [00500] step of the [Starch and Sucrose Metabolism] pathway (KEGG map number [2.7.1.4]). It catalyzes the conversion of [ATP + D-fructoseADP + D-fructose 6-phosphate]. The E. coli K12 MG1655 ortholog is predicted to be b1309, which has the gene identifier [ycjM]. We predict that Mrub__[ 3029] encodes the enzyme [Meiothermus ruber Sucrose phosphorylase] (DNA coordinates [3072410..3074080 on the forward strand]), which is the [00500] step of the [Starch and Sucrose Metabolism] pathway (KEGG map number [2.4.1.7 ]). It catalyzes the conversion of [sucrose + phosphate → β-D-fructofuranose + α-D-glucopyranose 1-phosphate]. The E. coli K12 MG1655 ortholog is predicted to be b0688, which has the gene identifier [pgm]. We predict that Mrub__[ 2052] encodes the enzyme [Meiothermus ruber phosphoglucomutase] (DNA coordinates [2088542..2090185 on the reverse strand], which is the [00500] step of the [Starch and Sucrose Metabolism] pathway (KEGG map number [5.4.2.2]). It catalyzes the conversion of [Alpha-D-glucose 1-phosphatealpha-D-glucose 6-phosphate]. The E. coli K12 MG1655 ortholog is predicted to be b0394, which has the gene identifier [mak].
Augustana Digital Commons Citation
Benstine, Max A. and Scott, Dr. Lori R.. "Mrub_3029, Mrub_2052, are predicted orthologs of b_0688, b_0394, while Mrub_0759 and Mrub_2365 are not predicted orthologs of b_1309, in Escherichia coli, which code for enzymes involved in starch and sucrose metabolism" (2017). Meiothermus ruber Genome Analysis Project.
https://digitalcommons.augustana.edu/biolmruber/27