BIOL-375: Molecular Genetics

Document Type

Student Paper

Streaming Media

Publication Date



Bioinformatics | Biology | Genomics | Molecular Genetics

Description, Abstract, or Artist's Statement

This project is part of the Meiothermus ruber genome analysis project, which uses a collection of online bioinformatics tools to predict gene function. We investigated the effect of temperature on the complexity of CRISPR/Cas systems in bacterial organisms across temperature classifications. We predict that temperature extremes would result in CRISPR/Cas systems with multiple operons, repeating cas genes, and complex systems. CRISPR/Cas systems can be classified into three types with a number of subtypes based on the CRISPR-associated genes, cas genes, present in a given organism. Our hypothesis is supported by the presence of multiple operons in thermophilic organisms based on data collect with bioinformatic tools KEGG and IMG/M. Organisms were predicted to have functional CRISPR/Cas operons, cas genes, or CRISPR arrays which suggest the presence of a CRISPR/Cas system.

Creative Commons License

Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 License.

Additional Files:

Midterm Paper .pdf (155 kB)